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pentobarbital will reduce the extent or effect of fedratinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Effect of coadministering a solid CYP3A4 inducer with fedratinib hasn't been studied.pentobarbital will lessen the extent or outcome of theophylline by affecting hepatic/intestinal enzyme CYP3… Read More